Sickle Cell Anaemia
Sickle cell disease is a genetic disorder which affects the red blood cells (RBCs) .The
RBCs of people with sickle cell disease contain a different form of hemoglobin called
haemoglobin ‘S’. This is an abnormal type of hemoglobin and RBCs containing this
hemoglobin become sickle shaped .They also become stiff ,and due their distorted shape
they have difficulty in passing through small blood vessels .When these sickle cells,
thus block the blood vessels less blood reaches that part of the body. Tissue that does not
receive the normal blood flow eventually gets damaged .This is the main cause of the
various complications including increased incidence of infections encountered in sickle
cell disease.
Sickle cell disease is an inherited, life long condition. People who have sickle cell
anaemia are born with it. They inherit two copies of the sickle gene from each parent.
Sickle cell disease is prevalent world over including India. The major features of the
sickle cell disease encountered in these patients include chronic fatigue, severe anaemia,
pain ,crises, bacterial infections, lung ,liver and heart injury, leg ulcers, damage to the eye
inflammation of the hands and feet, arthritis, spleenomegaly and chronic lung
infections etc.
A constant search is going on to find a substance which can stop sickling of RBCs or
which can at least offer lasting symptomatic relief to a patient with sickle cell disease.
[ Sickle Cell Anaemia - Clinical Features - Ayurvedic_view ]
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